The first smallpox vaccine changed the world—but we're still not sure what was in it
https://www.popsci.com/what-was-in-original-smallpox-vaccine
https://www.popsci.com/what-was-in-original-smallpox-vaccine
Smallpox vaccination of children was discontinued in the 1970's as it was believed that the disease had been eradicated. That makes millions susceptible if its used in a biological terrorist attack.
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